Rota-V-Aid

  • Single dose package including solvent
  • 2 doses package including solvent
  • 10 doses package. The solvent is supplied separately.
  • Store at room temperature (up to 25°C).
  • Avoid sunlight exposure and contact with disinfectants
  • Use within 6 hours after reconstitution. Store at 2-8°C during this time
SERUM INSTITUTE OF INDIA PVT. LTD.

Description

Live attenuated antiviral (oral) vaccine in lyophilized form, designed for active immunization of healthy infants to prevent gastroenteritis caused by rotavirus infection. Administered orally in a sequence of 3 doses.
Produced under license by Serum Institute of India Private Ltd., the world’s largest vaccines manufacturer. The vaccine has WHO qualification status and shows good results for several years in ~170 countries worldwide.
Internationally accepted vaccination schedule:

    • The first dose at 6 weeks of age;
    • The second dose in 4 weeks after the first one; the third dose in four weeks after the second one;
    • In the case of incomplete vaccination (the child spits up or regurgitates the vaccine), a single replacement dose may be administered during the same vaccination procedure upon the physician recommendation;
    • According to WHO recommendations, if routine childhood vaccination starts later than 6 weeks of age and/or with a dosage interval more than 4 weeks, live attenuated rotavirus (oral) vaccine can be administered separately or simultaneously with DPT, inactivated polio vaccine (IPV), oral polio vaccine (OPV), haemophilus influenzae type b conjugated vaccine (Hib), hepatitis B vaccine and pneumococcal vaccine. Live attenuated rotavirus (oral) vaccine does not place any restrictions on the feeding or drinking received by the infant (including breastfeeding), either before or after vaccination.

Each acceptable dose of the vaccine for humans contains 2.5 mL of:

    • Live, attenuated bovine/human rotavirus reassortant [G1, G2, G3, G4 and G9] ≥ 105.6 PFU/serotype (grown on VERO cells);
    • Sterile solvent (citrate bicarbonate buffer) prepared using 9.6 mg/mL citric acid monohydrate and 25.6 mg/mL sodium bicarbonate.

Frequently Asked Questions

Rotavirus infection is one of the most widespread infectious diseases. Children from 6 months to 5 years of age suffer most frequently. Children under 3 years of age are particularly susceptible to infection.

In typical cases, after an incubation period of 1-3 days, the disease begins suddenly with fever and vomiting, followed by watery diarrhoea.

Gastrointestinal symptoms usually disappear after 3-7 days, but can last up to 2-3 weeks. Rotavirus infection can be accompanied by the systemic complications such as febrile seizures, pneumonia, anaemia, pancreatitis, myocarditis and other medical conditions.
The main source of infection is a sick person or an asymptomatic carrier. The infectious agent is rotavirus. Rotaviruses are relatively stable in the environment, they do not die during water chlorination, survive up to 60 days in tap water, 10 to 30 days on various environmental objects, resistant to repeated freezing, relatively resistant to disinfectants.

There is no specific treatment for rotavirus infection. Only symptomatic treatment is available.
Given the high level of contagiousness of rotaviruses and the ineffectiveness of non-specific preventive measures (hygienic measures), as well as the lack of specific treatment, vaccination is currently recognized as the only effective method of combating rotavirus gastroenteritis.

The WHO recommends that rotavirus vaccines be included in the vaccination schedules in all countries as a priority, regardless of their level of development and wealth.

In the Russian Federation, vaccination against rotavirus infection is not included in the vaccination schedule, but in some regions of the Russian Federation vaccination is available to a wide range of children as part of regional vaccination programs.

The vaccination course of rotavirus vaccines available in the Russian Federation consists of 3 doses administered at intervals of at least 4 weeks, with vaccination starting at 6 weeks of age. The vaccination course must be completed when the child is 32 weeks old (8 months). Rotavirus vaccines can be administered at the same time as other vaccines in the vaccination schedule. Vaccines are administered orally and do not increase the child’s injection exposure.

The product has contraindications.
Consult a specialist before use.